Overview

BSA Blocking Solution, 5% - 5% BSA Blocking Solution is a routine immunoassay reagent used to block non-specific binding sites on membranes, plates, and tissue sections.


Use and Applications

  • Western blot membrane blocking
  • ELISA plate blocking and antibody dilution
  • IHC and IF blocking workflows
  • SDS-PAGE Hand-Casting Suite and IHC/IF Imaging Suite companion product

Specifications

ItemSpecification
Bottle50 mL or 100 mL sterile bottle
Primary vehicleTBS pH 7.6 with Tween 20
Secondary vehiclePBS variant available
PreservativeAzide-free by default

Composition 

ComponentAmount / concentrationFunction
BSA Fraction V5% w/v; CAS 9048-46-8Blocking protein
Tris-HCl / NaClTBS vehicleBuffer and ionic strength
Tween 200.05% optionalBackground reduction
Ultrapure waterq.s. to final volumeSolvent

Instruction

1Bring to room temperature and mix gently without foaming.
2Use directly for membrane or plate blocking according to the assay protocol.
3For antibody dilution, confirm the antibody datasheet supports BSA-containing diluent.
4Avoid returning used solution to the stock bottle.

Note

  • Phospho-specific antibody workflows often prefer BSA over milk because milk contains phosphoproteins that can increase background.

Cautions

Caution. BSA solutions are microbial-growth-prone without azide. Use aseptic technique and respect the opened-bottle shelf life.
Caution. Contains bovine-derived protein; confirm institutional and import documentation requirements where relevant.

Storage and Expiry · Safety

  • Store at 2-8 deg C.
  • After opening, use within the labelled period; single-use 50 mL format recommended for low-throughput labs.
  • Transport. Ships at ambient temperature in insulated packaging; brief transit temperature excursions are tolerated. Refrigerate at 2-8 deg C on receipt and protect from freezing.
  • Handling and PPE. Wear a laboratory coat, nitrile gloves, and safety glasses for routine handling. Contains bovine-derived protein; handle per institutional biological-material and import requirements. Consult the Safety Data Sheet before use.

References

  1. Safety Data Sheet: SDS draft to be finalised before commercial release.

Frequently Asked Questions

Q1. Why azide-free?
Azide can interfere with HRP-based detection and creates hazardous waste concerns. Azide-free product is broader-use if handled aseptically.