• Streptomycin sulfate | 100g

Streptomycin sulfate | 100g

AUD 89.00    Excl.GST
  • Product Code: CH-PP-SS01
  • Availability: 4-6 weeks

Tags: Streptomycin sulfate

Streptomycin sulfate | 100g

CAS Number:  3810-74-0

Linear Formula:  C21H39N7O12 · 1.5 H2SO4

Molecular Weight:  728.69

Storage: 2~8℃

Grade: High purity grade

Potency: 750-850mcg/mg

Moisture: ≤2.0%

Properties:

white to off-white powder.


Uses

  • Cell culture

Streptomycin is used to study mechanisms of streptomycin resistance and is often used together with penicillin and other agents to inhibit bacterial contamination in cell culture applications. It is recommended for use in molecular biology applications at 25-50μg/mL, in cell culture applications at 100 mg/L and in embryo culture at 50 mg/L.

  • Mode of Action:

Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from the imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation.

  • Protein purification

           When purifying protein from a biological extract, streptomycin sulfate can be added to remove nucleic acids and ribonuclear proteins. it can bind to ribosomes and precipitate out of solution, it serves as a method for removing rRNA, mRNA, and even DNA if the extract is from a prokaryote.


Cautions 

Stock requires storage at -20°C after the antibiotic has been configured into the solution.


This product is restricted to scientific research only and should not be used for clinical therapy or other purposes.